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The Science Behind OkiOne™

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The Science Behind OkiOne™

Built On evidence

Explore the growing body of research on Euglena and Paramylon, including studies investigating gut health, immune support, stress resilience, sleep quality and recovery.

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What is Euglena?

A Microalgae Unlike Any Other

A Microalgae Unlike Any Other

A Microalgae Unlike Any Other

Euglena is a nutrient-rich microalgae that combines characteristics of both plants and animals, naturally containing vitamins, minerals, amino acids, fatty acids, and a unique beta-glucan paramylon.

OkiOne™ is NURA’s branded Euglena ingredient, cultivated in Okinawa, Japan, and developed for use in supplements, beverages, functional foods, and other wellness applications.

The Clinically Studied Superfood for Daily Wellness

The Clinically Studied Superfood for Daily Wellness

Flowchart of OkiOne health benefits
Flowchart of OkiOne health benefits

Every system supports the next. Wellness is inter-connected.

Stronger Gut

Digestive health starts the story. A strong gut microbiome helps support digestion, nutrient absorption, and immune function: the foundation of overall wellness.

Greater Resilience

When your body is well-supported from within, it's better equipped to adapt to everyday stress, strengthen immune response, and maintain balance.

Better Sleep

By supporting interconnected systems like gut health and stress resilience, OkiOne™ helps promote restorative sleep to help you feel your best every day of the week.

Graph of OkiOne gut health benefits from a clinical study

The Gut is Where True Health Begins

The Gut is Where True Health Begins

How does OkiOne™ support gut health?

How does OkiOne™ support gut health?

The gut microbiome plays a central role in digestion, immune function, and overall wellness. Research on OkiOne™ has shown its potential to support beneficial gut bacteria, including butyrate-producing microbes, while helping maintain healthy digestive function and bowel regularity. *

Research Highlights

  • Supports the growth of beneficial butyrate-producing bacteria*

  • Helps maintain healthy bowel regularity*

  • Supports stool volume and frequency*

Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

The gut microbiome plays a central role in digestion, immune function, and overall wellness. Research on OkiOne™ has shown its potential to support beneficial gut bacteria, including butyrate-producing microbes, while helping maintain healthy digestive function and bowel regularity.

Research Highlights

  • Supports the growth of beneficial butyrate-producing bacteria

  • Helps maintain healthy bowel regularity


Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

The gut microbiome plays a central role in digestion, immune function, and overall wellness. Research on OkiOne™ has shown its potential to support beneficial gut bacteria, including butyrate-producing microbes, while helping maintain healthy digestive function and bowel regularity. *

Research Highlights

  • Supports the growth of beneficial butyrate-producing bacteria*

  • Helps maintain healthy bowel regularity*

  • Supports stool volume and frequency*

Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Everyday Immune Support

How does OkiOne™ support the immune system?

A healthy immune system helps the body respond to everyday challenges. Clinical research has investigated OkiOne™ and its unique beta-1,3-glucan, Paramylon, for its ability to support healthy immune function and seasonal wellness.

Research Highlights

  • Supports a healthy immune response*

  • Helps maintain more symptom-free days during cold and flu season*

  • Supports overall immune resilience*

Clinical Research: Human clinical study
Studied Dosage: 1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Everyday Immune Support

How does OkiOne™ support the immune system?

A healthy immune system helps the body respond to everyday challenges. Clinical research has investigated OkiOne™ and its unique beta-1,3-glucan, Paramylon, for its ability to support healthy immune function and seasonal wellness.

Research Highlights

  • Supports a healthy immune response

  • Helps maintain more symptom-free days during cold and flu season

  • Supports overall immune resilience


Clinical Research: Human clinical study
Studied Dosage: 1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Everyday Immune Support

How does OkiOne™ support the immune system?

A healthy immune system helps the body respond to everyday challenges. Clinical research has investigated OkiOne™ and its unique beta-1,3-glucan, Paramylon, for its ability to support healthy immune function and seasonal wellness.

Research Highlights

  • Supports a healthy immune response*

  • Helps maintain more symptom-free days during cold and flu season*

  • Supports overall immune resilience*

Clinical Research: Human clinical study
Studied Dosage: 1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Graph of OkiOne immune health benefits from a clinical study
Graph of OkiOne stress resilience benefits from a clinical study

Calm, Focused Wellness

Calm, Focused Wellness

Calm, Focused Wellness

How does OkiOne™ support the mind?

Managing everyday stress is an important part of long-term health. Clinical research has explored how Euglena may help support healthy autonomic nervous system balance while promoting a calm and focused response during mentally demanding tasks. *

Research Highlights

  • Supports healthy autonomic nervous system balance*

  • Promotes a calm, focused response to everyday stress*

  • Helps maintain a positive mood throughout the day*

  • Supports overall emotional well-being*

Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Managing everyday stress is an important part of long-term health. Clinical research has explored how Euglena may help support healthy autonomic nervous system balance while promoting a calm and focused response during mentally demanding tasks.


Research Highlights

  • Supports autonomic nervous system balance

  • Promotes a calm, focused stress response

  • Helps maintain a positive mood

  • Supports overall emotional well-being


Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Managing everyday stress is an important part of long-term health. Clinical research has explored how Euglena may help support healthy autonomic nervous system balance while promoting a calm and focused response during mentally demanding tasks. *

Research Highlights

  • Supports healthy autonomic nervous system balance*

  • Promotes a calm, focused response to everyday stress*

  • Helps maintain a positive mood throughout the day*

  • Supports overall emotional well-being*

Clinical Research: Human and in vitro studies
Studied Dosage: 0.5–2 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Wake Up Feeling Refreshed

Wake Up Feeling Refreshed

Wake Up Feeling Refreshed

How does OkiOne™ support Sleep?

Restorative sleep is one of the foundations of healthy aging. Research suggests Euglena may help support healthy sleep quality, contributing to improved recovery and overall well-being. *

Research Highlights

  • Supports healthy sleep quality and greater sleep satisfaction*

  • Helps reduce morning sleepiness*

Clinical Research: Human clinical study
Studied Dosage: 0.5–1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Restorative sleep is one of the foundations of healthy aging. Research suggests Euglena may help support healthy sleep quality, contributing to improved recovery and overall well-being.


Research Highlights

  • Supports greater sleep satisfaction and quality

  • Helps reduce morning sleepiness


Clinical Research: Human clinical study
Studied Dosage: 0.5–1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Restorative sleep is one of the foundations of healthy aging. Research suggests Euglena may help support healthy sleep quality, contributing to improved recovery and overall well-being. *

Research Highlights

  • Supports healthy sleep quality and greater sleep satisfaction*

  • Helps reduce morning sleepiness*

Clinical Research: Human clinical study
Studied Dosage: 0.5–1 g daily


Nakashima A, et al. Sci Rep. 2021 ; 11 (1) : 1074.

Graph of OkiOne sleep benefits from a clinical study